SCHEMBL19997052

SCHEMBL19997052

c1ccc2c(c1)CCc1ccccc1C2C1c2ccccc2CCc2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.56
RET P07949 1/20 0.56
ACP3 P15309 1/20 0.52
SIGMAR1 Q99720 2/20 0.47
IDO1 P14902 3/20 0.46
PDPK1 O15530 1/20 0.46
PRCP P42785 2/20 0.45
CYP11B2 P19099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9385590 0.83 ACP3 (0.48) HTR2ARETACP3SIGMAR1IDO1
SCHEMBL23832807 0.81 HTR2A (0.45) HTR2ARETACP3SIGMAR1IDO1
SCHEMBL18045643 0.81 HTR2A (0.45) HTR2ARETACP3SIGMAR1IDO1
SCHEMBL30096678 0.81 HTR2A (0.45) HTR2ARETACP3SIGMAR1IDO1
SCHEMBL440138 0.80 HTR2A (0.54) HTR2ARETACP3IDO1PDPK1
SCHEMBL506278 0.80 ACP3 (0.56) HTR2ARETACP3IDO1PDPK1
SCHEMBL29793145 0.80 HTR2A (0.54) HTR2ARETACP3IDO1PDPK1
SCHEMBL12935438 0.79 RET (0.40) HTR2ARETACP3SIGMAR1IDO1
SCHEMBL7871424 0.78 HTR2A (0.52) HTR2ARETACP3IDO1PDPK1
SCHEMBL113822 0.78 HTR2A (0.73) HTR2ARETACP3IDO1PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9929363-B2 Composition and synthesis of aggregation-induced emission materials THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2018-03-27 US disclosed