SCHEMBL19997972

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18435722	0.92	KDM4E (0.41)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL17367755	0.89	KDM4E (0.46)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL17990266	0.89	ALDH1A1 (0.39)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL19986065	0.88	MEN1 (0.36)	MEN1KMT2ACYP2C19ALOX5
	SCHEMBL19046688	0.88	MEN1 (0.36)	MEN1KMT2ACYP2C19ALOX5
	SCHEMBL19997973	0.87	KDM4E (0.41)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL15462296	0.87	KDM4E (0.47)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL17433077	0.85	KDM4E (0.39)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL18058131	0.85	CA9 (0.36)	KDM4EATML3MBTL1ALDH1A1PPARG
	SCHEMBL27427097	0.85	KDM4E (0.46)	KDM4EATML3MBTL1ALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.