Sugi Predict

Sugi Predict / Compounds / SCHEMBL19997974

SCHEMBL19997974

SCHEMBL19997974

c1ccc(-n2c3ccccc3c3c4c5ccccc5c5ccccc5c4c4c5ccccc5n(-c5ccc6oc7ccccc7c6c5)c4c32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.40
▸ ATM Q13315 1/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.39
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ MEN1 O00255 2/20 0.39
▸ KMT2A Q03164 2/20 0.39
▸ NPC1 O15118 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ LMNA P02545 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ TSHR P16473 1/20 0.36
▸ BRCA1 P38398 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ AHR P35869 1/20 0.36
▸ CA12 O43570 2/20 0.34
▸ CA9 Q16790 2/20 0.34
▸ SIRT2 Q8IXJ6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17245532 0.95 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL21137692 0.93 KDM4E (0.41) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL19997971 0.92 KDM4E (0.40) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17123108 0.92 KDM4E (0.42) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL19046681 0.91 MAPT (0.40) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL21109302 0.91 KDM4E (0.43) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17405925 0.89 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL17406175 0.89 KDM4E (0.37) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL19986052 0.88 ALDH1A1 (0.38) KDM4EALDH1A1SMN1; SMN2MEN1KMT2A
SCHEMBL17123079 0.88 KDM4E (0.39) KDM4EATML3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10032999-B2 Compound for organic optoelectric device, composition for organic optoelectric device and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2018-07-24 — — US disclosed
US-20180090690-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10032999-B2 Compound for organic optoelectric device, composition for organic optoelectric device and organic optoelectric device and display device OXER1, OCIAD1, OR10J3 KDM4E 3867/4885ATM 3788/4885L3MBTL1 4497/4885
US-20180090690-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 KDM4E 3867/4885ATM 3788/4885L3MBTL1 4497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.