Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29038034 | 0.80 | ZDHHC7 (0.48) | ZDHHC7POLBMMEFOLH1TAS1R3 | |
| SCHEMBL936362 | 0.80 | ZDHHC7 (0.48) | ZDHHC7POLBMMEFOLH1TAS1R3 | |
| SCHEMBL1415280 | 0.73 | ZDHHC7 (0.54) | ZDHHC7MME | |
| SCHEMBL6683720 | 0.72 | ZDHHC7 (0.48) | ZDHHC7POLBMMETAS1R3TAS1R1 | |
| SCHEMBL13620362 | 0.70 | ZDHHC7 (0.57) | ZDHHC7MMEFOLH1 | |
| SCHEMBL106430 | 0.70 | ZDHHC7 (0.47) | ZDHHC7MMETAS1R3TAS1R1 | |
| SCHEMBL9062988 | 0.69 | TDP1 (0.30) | — | |
| SCHEMBL5965786 | 0.69 | ZDHHC7 (0.65) | ZDHHC7 | |
| SCHEMBL1415237 | 0.69 | ZDHHC7 (0.65) | ZDHHC7 | |
| SCHEMBL22162843 | 0.69 | ZDHHC7 (0.46) | ZDHHC7MMETAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054300-A1 | CHOLIC ACID DERIVATIVE FREE ALKALI, CRYSTALLINE FORM, PREPARATION METHODS THEREFOR AND APPLICATIONS THEREOF | 江苏豪森药业集团有限公司 | 2018-03-29 | — | — | WO | disclosed |