SCHEMBL1415280

SCHEMBL1415280

COC(=O)C(Br)CC(Br)C(=O)OC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.42
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA14 Q9ULX7 2/20 0.36
TSHR P16473 4/20 0.35
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 3/20 0.33
CA12 O43570 1/20 0.33
MME P08473 1/20 0.32
MGAM O43451 2/20 0.32
GAA P10253 2/20 0.32
SI P14410 2/20 0.32
MGAM2 Q2M2H8 2/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27575981 0.91 ZDHHC7 (0.47) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL29038034 0.87 ZDHHC7 (0.48) ZDHHC7SMN1; SMN2CA14CA12MME
SCHEMBL6683720 0.87 ZDHHC7 (0.48) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL936362 0.87 ZDHHC7 (0.48) ZDHHC7SMN1; SMN2CA14CA12MME
SCHEMBL106430 0.85 ZDHHC7 (0.47) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL9352213 0.85 ZDHHC7 (0.43) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL22162842 0.84 ZDHHC7 (0.46) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL22162843 0.84 ZDHHC7 (0.46) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL1008732 0.84 ZDHHC7 (0.50) ZDHHC7SMN1; SMN2CA1CA2CA14
SCHEMBL5965786 0.83 ZDHHC7 (0.65) ZDHHC7SMN1; SMN2CA1CA2CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661541-A Synthesis method of 6- (tert-butoxycarbonyl) -3, 6-diazabicyclo [3.1.1] heptane 上海馨远医药科技有限公司 2025-03-21 CN disclosed
US-11649244-B2 Method for synthesizing diaza-bridged compound and a diaza-bridged compound LinkChem Co., Ltd., Shanghai (CN) 2023-05-16 US disclosed
CN-114516882-A Preparation method of cycloalkane tetracarboxylic dianhydride 烟台弘邦医药科技有限公司 2022-05-20 CN disclosed
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
WO-2014011863-A1 METHOD OF TREATMENT WITH 3-CYCLOPROPYLCARBONYL-3,6-DIAZABICYCLO[3.1.1]HEPTANE TARGACEPT, INC. (US) 2014-01-16 WO disclosed
WO-2012125518-A1 SALT FORMS OF 3 - CYCLOPROPYLCARBONYL - 3, 6 - DIAZABICYCLO [3.1.1] HEPTANE TARGACEPT, INC. (US) 2012-09-20 WO disclosed
EP-1714992-B1 THERMOPLASTIC ELASTOMER COMPOSITION AND MOLDED ARTICLE KANEKA CORP (JP) 2011-03-16 EP disclosed
EP-1398353-B1 THERMOPLASTIC RESIN COMPOSITION KANEKA CORP (JP) 2010-10-13 EP disclosed
US-7799869-B2 Thermoplastic elastomer composition and molded article KANEKA CORPORATION (JP) 2010-09-21 US disclosed
US-7732529-B2 Thermoplastic elastomer composition and molded article KANEKA CORPORATION (JP) 2010-06-08 US disclosed
EP-1398353-A1 THERMOPLASTIC RESIN COMPOSITION Kaneka Corporation (JP) 2004-03-17 EP disclosed
EP-0607374-B1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS PO HANG IRON & STEEL (KR) 1999-04-07 EP disclosed
US-5700817-A Cyclic lipid derivatives as potent PAF antagonists POHANG IRON & STEEL CO., LTD. (KR) 1997-12-23 US disclosed
US-5610310-A Cyclic lipid derivatives as potent PAF antagonists POHANG IRON & STEEL CO., LTD (KR) 1997-03-11 US disclosed
EP-0299513-B1 Azetidine derivatives, compositions and their use FIDIA GEORGETOWN INST (US) 1994-10-05 EP disclosed
EP-0607374-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-07-27 EP disclosed
WO-1994000447-A1 NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS POHANG IRON & STEEL CO., LTD. (KR) 1994-01-06 WO disclosed
US-4990504-A Modulate excitatory amino acid receptor system FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1991-02-05 US disclosed
US-4946839-A ALZHEIMER'S DISEASE FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1990-08-07 US disclosed
EP-0299513-A1 Azetidine derivatives, compositions and their use FIDIA-GEORGETOWN INSTITUTE FOR THE NEUROSCIENCES (US) 1989-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649244-B2 Method for synthesizing diaza-bridged compound and a diaza-bridged compound DGAT2, NOS2, ABL1 ZDHHC7 801/4885SMN1; SMN2 1887/4885CA1 2270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.