Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 4/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16476778 | 0.80 | CNR1 (0.38) | TSHRMAPK1CNR1CNR2PKM | |
| SCHEMBL17481288 | 0.77 | IKBKB (0.36) | TSHRMAPK1PKMIKBKBLIMK1 | |
| SCHEMBL15472486 | 0.77 | ALDH1A1 (0.41) | CNR1CNR2IKBKBLIMK1ALDH1A1 | |
| SCHEMBL5519898 | 0.77 | CNR1 (0.49) | TSHRCNR1CNR2IKBKBLIMK1 | |
| SCHEMBL16476769 | 0.76 | HPGD (0.38) | TSHRMAPK1CNR1CNR2ALDH1A1 | |
| SCHEMBL22762361 | 0.70 | — | — | |
| SCHEMBL13487529 | 0.70 | — | — | |
| SCHEMBL17483800 | 0.69 | ALDH1A1 (0.39) | IKBKBLIMK1ALDH1A1HSD17B10 | |
| SCHEMBL19059552 | 0.68 | — | — | |
| SCHEMBL3513465 | 0.65 | CNR1 (0.37) | CNR1CNR2IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086748-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-03-29 | — | — | US | disclosed |
| US-20180086748-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086748-A1 | HETEROAROMATIC COMPOUNDS AS BTK INHIBITORS | BTK, SYK, LCK | TSHR 2925/4885MAPK1 954/4885CNR1 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.