SCHEMBL20000026

SCHEMBL20000026

C[Si](C)(CCCOCCO)O[Si](C)(C)O[Si](CCC(F)(F)F)(CCC(F)(F)F)O[Si](C)(C)CCCOCCO

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20000017 0.89
SCHEMBL20000010 0.87
SCHEMBL20000022 0.84
SCHEMBL63384 0.82 TSHR (0.46) TSHRMEN1THRBHTTKMT2A
SCHEMBL31348327 0.82 TSHR (0.46) TSHRMEN1THRBHTTKMT2A
SCHEMBL19039345 0.82 TSHR (0.46) TSHRMEN1THRBHTTKMT2A
SCHEMBL26921080 0.82 TSHR (0.46) TSHRMEN1THRBHTTKMT2A
SCHEMBL19822567 0.80 MEN1 (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL31187421 0.80 MEN1 (0.45) TSHRMEN1THRBHTTKMT2A
SCHEMBL10301166 0.80 MEN1 (0.45) TSHRMEN1THRBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086874-A1 SILICONE-MODIFIED POLYURETHANE-BASED FIBER AND METHOD FOR MANUFACTURING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed