SCHEMBL63384

SCHEMBL63384

C[Si](C)(CCCOCCO)O[Si](C)(C)O[Si](C)(C)CCCOCCO

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
THRB P10828 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31348327 1.00 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL26921080 1.00 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL19039345 1.00 TSHR (0.46) TSHRMEN1KMT2ATHRBHTT
SCHEMBL10301166 0.98 MEN1 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL31187424 0.98 MEN1 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL31187421 0.98 MEN1 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL19822567 0.98 MEN1 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL31187428 0.98 MEN1 (0.45) TSHRMEN1KMT2ATHRBHTT
SCHEMBL20023895 0.96 MEN1 (0.44) TSHRMEN1KMT2ATHRBHTT
SCHEMBL18233785 0.96 TSHR (0.43) TSHRMEN1KMT2ATHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747005-A1 METHOD FOR THE MANUFACTURE OF A CATALYTIC FILTER Johnson Matthey Public Limited Company (GB) 2026-05-27 EP disclosed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
WO-2025202628-A1 METHOD OF FORMING AN INORGANIC OXIDE COATING ON A MONOLITH ARTICLE JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2025-10-02 WO disclosed
EP-4624045-A1 METHOD OF FORMING AN INORGANIC OXIDE COATING ON A MONOLITH ARTICLE Johnson Matthey Public Limited Company (GB) 2025-10-01 EP disclosed
EP-3233981-B1 PROCESS FOR MAKING A WATERBORNE DISPERSION COMPRISING A CATIONIC POLYAMIDE POLYMER LUBRIZOL ADVANCED MAT INC (US) 2025-07-23 EP disclosed
CN-120202054-A Coating on monolithic articles 庄信万丰股份有限公司 2025-06-24 CN disclosed
CN-119866241-A Coating on monolithic articles 庄信万丰股份有限公司 2025-04-22 CN disclosed
CN-119730960-A Method of forming inorganic oxide coating on monolithic article 庄信万丰股份有限公司 2025-03-28 CN disclosed
WO-2025022090-A1 METHOD FOR THE MANUFACTURE OF A CATALYTIC FILTER JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2025-01-30 WO disclosed
US-12201969-B2 Method of forming an inorganic oxide coating on a monolith article JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2025-01-21 US disclosed
US-8128919-B2 Long-wearing cosmetic composition AVON PRODUCTS, INC (US) 2012-03-06 US disclosed
US-20110190455-A1 POLYDIALKYLSILOXANE-BRIDGED BI-PHOTOCHROMIC MOLECULES Vivimed Labs Europe Ltd. (GB) 2011-08-04 US disclosed
US-7862805-B2 Cosmetic composition forming after application a supramolecular polymer L'OREAL (FR) 2011-01-04 US disclosed
US-20100310647-A1 Enzymatic Synthesis of Polymers UNIVERSITY OF MASSACHUSETTS (US) 2010-12-09 US disclosed
US-20100247466-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER L'OREAL (FR) 2010-09-30 US disclosed
US-20080293844-A1 Gels AORTECH BIOMATERIALS PTY LTD (AU) 2008-11-27 US disclosed
US-20080107695-A1 Includes film-forming silicone-containing polyurethane AVON PRODUCTS, INC. 2008-05-08 US disclosed
US-7326746-B2 Curable electron donor compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2008-02-05 US disclosed
US-20070154440-A1 Long wearing cosmetic compositions AVON PRODUCTS, INC. 2007-07-05 US disclosed
US-20070060683-A1 Curable electron donor compositions HENKEL AG & CO. KGAA (DE) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154440-A1 Long wearing cosmetic compositions CUTA, PUF60, LPL TSHR 1620/4885MEN1 1089/4885KMT2A 2780/4885
US-20100310647-A1 Enzymatic Synthesis of Polymers PNKP, MGAM, COASY TSHR 4699/4885MEN1 2451/4885KMT2A 1762/4885
US-20080107695-A1 Includes film-forming silicone-containing polyurethane CUTA, ALG3, SMYD3 TSHR 2288/4885MEN1 61/4885KMT2A 553/4885
US-20110190455-A1 POLYDIALKYLSILOXANE-BRIDGED BI-PHOTOCHROMIC MOLECULES UACA, DCLRE1A, RAD54L TSHR 3623/4885MEN1 3382/4885KMT2A 2348/4885
US-20100247466-A1 COSMETIC COMPOSITION FORMING AFTER APPLICATION A SUPRAMOLECULAR POLYMER KRT18, CUTA, DSG1 TSHR 3421/4885MEN1 2080/4885KMT2A 2307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.