Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12546076 | 0.98 | MAOA (0.33) | MAOAHTR2AHRH1KIF11KCNH2 | |
| SCHEMBL13878406 | 0.97 | MAOA (0.32) | MAOAHTR2AHRH1KIF11KCNH2 | |
| SCHEMBL676715 | 0.94 | MAOA (0.31) | MAOAHTR2AHRH1 | |
| SCHEMBL13100638 | 0.92 | HTR2A (0.33) | MAOAHTR2AHRH1 | |
| SCHEMBL15077869 | 0.91 | — | — | |
| SCHEMBL18179461 | 0.89 | TAAR1 (0.32) | HTR2ATAAR1KDM4E | |
| SCHEMBL20000047 | 0.88 | — | — | |
| SCHEMBL20565391 | 0.87 | MAOA (0.35) | MAOAHTR2AHRH1KIF11KCNH2 | |
| SCHEMBL1240249 | 0.86 | MAOA (0.34) | MAOAHTR2AHRH1KIF11KCNH2 | |
| SCHEMBL26017954 | 0.85 | HTR2A (0.30) | HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086874-A1 | SILICONE-MODIFIED POLYURETHANE-BASED FIBER AND METHOD FOR MANUFACTURING SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-03-29 | — | — | US | disclosed |