SCHEMBL20000080

SCHEMBL20000080

CC(=O)Oc1c(C)c(N)c(C)c(N)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
POLB P06746 1/20 0.37
LMNA P02545 2/20 0.37
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
PREP P48147 2/20 0.34
CELA1 Q9UNI1 1/20 0.34
TOP1 P11387 3/20 0.34
CA2 P00918 1/20 0.33
MAPK1 P28482 1/20 0.33
ACHE P22303 2/20 0.32
BACE1 P56817 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9507056 0.82 LMNA (0.44) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL5865884 0.82 LMNA (0.44) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL13134484 0.79 LMNA (0.42) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL1131401 0.78 POLB (0.34) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL4631442 0.77 KDM4E (0.45) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL20075881 0.73 PREP (0.44) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL10938410 0.71 POLB (0.49) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL21291912 0.71 KDM4E (0.37) KDM4EHSD17B10ALDH1A1HPGDPOLB
SCHEMBL9507051 0.70 KDM4E (0.36) KDM4EHSD17B10ALDH1A1HPGDPOLB
Ammonia Solution, Strong SCHEMBL28214056 0.70 POLB (0.47) KDM4EHSD17B10ALDH1A1HPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10974207-B2 Gas separation membrane, gas separation membrane module, and gas separation device FUJIFILM CORPORATION (JP) 2021-04-13 US disclosed
US-10537859-B2 Gas separation membrane, gas separation module, gas separation device, gas separation method, and polyimide compound FUJIFILM CORPORATION (JP) 2020-01-21 US disclosed
US-20190091635-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-28 US disclosed
US-20190076777-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MEMBRANE MODULE, AND GAS SEPARATION DEVICE FUJIFILM CORPORATION (JP) 2019-03-14 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed
US-20180085716-A1 GAS SEPARATION MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION DEVICE, GAS SEPARATION METHOD, AND POLYIMIDE COMPOUND FUJIFILM CORPORATION (JP) 2018-03-29 US disclosed