Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 2/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 9/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.32 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000528 | 0.85 | ACACB (0.36) | ACACBPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20000526 | 0.80 | MAP3K7 (0.40) | MAP3K7TAB1ACACBNUDT1 | |
| SCHEMBL38661744 | 0.72 | PDPK1 (0.37) | MAPTSMN1; SMN2PI4KAPI4K2BPI4K2A | |
| SCHEMBL31438493 | 0.69 | SSTR4 (0.36) | ACACBPTGS2 | |
| SCHEMBL29023534 | 0.69 | SSTR4 (0.36) | ACACBPTGS2 | |
| SCHEMBL15741407 | 0.66 | — | — | |
| SCHEMBL25190847 | 0.66 | SSTR4 (0.41) | MAP3K7TAB1ACACBPTGS2 | |
| SCHEMBL31438598 | 0.66 | SSTR4 (0.41) | MAP3K7TAB1ACACBPTGS2 | |
| SCHEMBL18809713 | 0.65 | — | — | |
| SCHEMBL25194810 | 0.65 | SSTR4 (0.38) | MAP3K7TAB1ACACBPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997024-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |