Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17812896 | 1.00 | REN (0.82) | REN | |
| SCHEMBL799679 | 1.00 | REN (0.82) | REN | |
| SCHEMBL13486098 | 1.00 | REN (0.82) | REN | |
| SCHEMBL13906294 | 0.95 | REN (0.81) | REN | |
| SCHEMBL7379865 | 0.94 | REN (0.83) | REN | |
| SCHEMBL7545740 | 0.92 | REN (0.82) | REN | |
| SCHEMBL14190816 | 0.92 | REN (0.82) | REN | |
| SCHEMBL12957327 | 0.91 | REN (0.78) | REN | |
| SCHEMBL881010 | 0.91 | REN (0.80) | REN | |
| SCHEMBL1941950 | 0.90 | REN (1.00) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2956464-B1 | SUBSTITUTED BISPHENYL BUTANOIC PHOSPHONIC ACID DERIVATIVES AS NEP (NEUTRAL ENDOPEPTIDASE) INHIBITORS | NOVARTIS AG (CH) | 2018-03-28 | — | — | EP | disclosed |