Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 18/20 | 0.64 |
| ▸ | FPR2 | P25090 | 10/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988375 | 1.00 | FPR1 (0.64) | FPR1FPR2PDE4B | |
| SCHEMBL19972293 | 0.86 | FPR1 (0.69) | FPR1FPR2 | |
| SCHEMBL19988359 | 0.82 | FPR1 (0.62) | FPR1FPR2PDE4B | |
| SCHEMBL20001242 | 0.78 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL19988381 | 0.78 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL19988703 | 0.78 | FPR1 (0.62) | FPR1FPR2 | |
| SCHEMBL19972244 | 0.78 | FPR1 (0.83) | FPR1FPR2 | |
| SCHEMBL19972243 | 0.78 | FPR1 (0.83) | FPR1FPR2 | |
| SCHEMBL20001254 | 0.78 | FPR1 (0.83) | FPR1FPR2 | |
| SCHEMBL19988376 | 0.78 | FPR1 (1.00) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |