Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228071 | 0.88 | KMT2A (0.34) | KMT2ADRD4KDM4EMEN1CARM1 | |
| SCHEMBL14228074 | 0.86 | KMT2A (0.36) | KMT2ADRD4KDM4EMEN1RAD52 | |
| SCHEMBL12739148 | 0.84 | KMT2A (0.32) | KMT2ADRD4KDM4EMEN1RAD52 | |
| SCHEMBL12739672 | 0.82 | KMT2A (0.33) | KMT2ADRD4KDM4EMEN1CARM1 | |
| SCHEMBL17783195 | 0.79 | KMT2A (0.59) | KMT2ADRD4KDM4E | |
| SCHEMBL14228072 | 0.77 | KDM4E (0.35) | KMT2AKDM4EMEN1RAD52 | |
| SCHEMBL13063841 | 0.73 | POLB (0.38) | KMT2AKDM4EMEN1 | |
| SCHEMBL13063786 | 0.72 | KMT2A (0.36) | KMT2AKDM4EMEN1 | |
| SCHEMBL14195803 | 0.69 | HPGD (0.46) | KMT2AKDM4EMEN1 | |
| SCHEMBL12714284 | 0.68 | KMT2A (0.60) | KMT2ADRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10695446-B2 | Composition and method for detecting hypoxia | VANDERBILT UNIVERSITY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20180085475-A1 | Composition and Method for Detecting Hypoxia | VANDERBILT UNIVERSITY | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10695446-B2 | Composition and method for detecting hypoxia | HIF1A, HIF1AN, HYOU1 | KMT2A 888/4885DRD4 4831/4885KDM4E 1640/4885 |
| US-20180085475-A1 | Composition and Method for Detecting Hypoxia | HIF1A, HIF1AN, HYOU1 | KMT2A 888/4885DRD4 4831/4885KDM4E 1640/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.