Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2239665 | 1.00 | SLC22A2 (0.36) | SLC22A2SLC47A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL21401948 | 1.00 | SLC22A2 (0.36) | SLC22A2SLC47A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL20042215 | 0.81 | SMN1; SMN2 (0.34) | SLC22A2SLC47A1MAPTSMN1; SMN2 | |
| SCHEMBL20042213 | 0.81 | SMN1; SMN2 (0.34) | SLC22A2SLC47A1MAPTSMN1; SMN2 | |
| SCHEMBL20042216 | 0.81 | SMN1; SMN2 (0.34) | SLC22A2SLC47A1MAPTSMN1; SMN2 | |
| SCHEMBL191884 | 0.79 | GRIN2D (0.41) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL1054419 | 0.79 | — | — | |
| SCHEMBL25237741 | 0.78 | — | — | |
| SCHEMBL31345052 | 0.78 | — | — | |
| SCHEMBL10791429 | 0.75 | SLC22A2 (0.36) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057973-A1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2018-03-29 | — | — | WO | disclosed |