Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12604823 | 0.85 | PTPN1 (0.47) | PTPN1KDM4ENPSR1ATMMEN1 | |
| SCHEMBL20002044 | 0.84 | PTPN1 (0.46) | PTPN1KDM4ENPSR1ATMMEN1 | |
| SCHEMBL21049581 | 0.79 | PTPN1 (0.41) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL21049548 | 0.79 | PTPN1 (0.41) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL21049569 | 0.79 | PTPN1 (0.41) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL22189081 | 0.79 | PTPN1 (0.41) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL15157507 | 0.74 | PTPN1 (0.56) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL22189077 | 0.74 | PTPN1 (0.44) | PTPN1KDM4ENPSR1ATMMEN1 | |
| Iodide SCHEMBL5143882 | 0.73 | PTPN1 (0.58) | PTPN1KDM4EMAPK1NPSR1ATM | |
| SCHEMBL22189012 | 0.69 | NPSR1 (0.43) | PTPN1KDM4EMAPK1NPSR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2392606-B1 | PREPARATION METHOD OF POLYLACTIC ACID BY CATALYSIS OF CARBENE DERIVATIVES | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2018-03-28 | — | — | EP | disclosed |