Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042246 | 0.87 | TDO2 (0.37) | TDO2NOS1 | |
| SCHEMBL20042273 | 0.83 | TDO2 (0.41) | TDO2NOS1 | |
| SCHEMBL20001907 | 0.81 | TDO2 (0.41) | TDO2NOS1 | |
| SCHEMBL20043557 | 0.79 | TDO2 (0.37) | TDO2NOS1 | |
| SCHEMBL20001778 | 0.79 | TDO2 (0.37) | TDO2NOS1 | |
| SCHEMBL20001913 | 0.78 | TDO2 (0.38) | TDO2NOS1 | |
| SCHEMBL20002555 | 0.77 | TDO2 (0.36) | TDO2NOS1 | |
| SCHEMBL20002073 | 0.75 | TDO2 (0.39) | TDO2NOS1 | |
| SCHEMBL19995846 | 0.75 | TDO2 (0.39) | TDO2NOS1 | |
| SCHEMBL20002079 | 0.75 | TDO2 (0.34) | TDO2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183145-A1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| WO-2018057973-A1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2018-03-29 | — | — | WO | disclosed |