Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002091 | 0.95 | TDO2 (0.38) | TDO2NOS1 | |
| SCHEMBL20042293 | 0.93 | TDO2 (0.40) | TDO2NOS1 | |
| SCHEMBL20002316 | 0.93 | TDO2 (0.40) | TDO2NOS1 | |
| SCHEMBL20002601 | 0.93 | TDO2 (0.40) | TDO2NOS1 | |
| SCHEMBL20042274 | 0.90 | TDO2 (0.39) | TDO2NOS1 | |
| SCHEMBL20002233 | 0.88 | TDO2 (0.37) | TDO2NOS1 | |
| SCHEMBL20001893 | 0.81 | TDO2 (0.36) | TDO2NOS1 | |
| SCHEMBL20002048 | 0.80 | TDO2 (0.35) | TDO2NOS1 | |
| SCHEMBL20002085 | 0.80 | TDO2 (0.35) | TDO2NOS1 | |
| SCHEMBL20002095 | 0.80 | TDO2 (0.40) | TDO2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057973-A1 | COMPOUNDS AND METHODS FOR IDO AND TDO MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2018-03-29 | — | — | WO | disclosed |