Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20255525 | 0.80 | FFAR3 (0.62) | FFAR3CYP2C9CYP2C19CYP1A2SLC1A2 | |
| SCHEMBL18084129 | 0.80 | FFAR3 (0.36) | FFAR3CYP2C9CYP2C19CYP19A1CYP1A2 | |
| SCHEMBL1468704 | 0.80 | FFAR3 (0.62) | FFAR3CYP2C9CYP2C19CYP1A2SLC1A2 | |
| SCHEMBL10203449 | 0.80 | FFAR3 (0.62) | FFAR3CYP2C9CYP2C19CYP1A2SLC1A2 | |
| SCHEMBL17110186 | 0.78 | FFAR3 (0.35) | FFAR3CYP19A1SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL5729318 | 0.78 | FFAR3 (0.35) | FFAR3CYP2C9CYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL17298612 | 0.78 | FFAR3 (0.35) | FFAR3CYP19A1SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL19706806 | 0.78 | TDP1 (0.35) | FFAR3CYP2C9CYP2C19PKMCYP1A2 | |
| SCHEMBL811021 | 0.78 | — | — | |
| SCHEMBL16892291 | 0.76 | APLNR (0.44) | FFAR3CYP2C19KDM4ECYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |