Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 14/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003023 | 0.86 | RORC (0.64) | RORC | |
| SCHEMBL20003108 | 0.85 | RORC (0.47) | RORCPOLBGAAMEN1KMT2A | |
| SCHEMBL20002621 | 0.85 | RORC (0.48) | RORCPOLBGAAKMT2AOPRL1 | |
| SCHEMBL20002760 | 0.84 | RORC (0.48) | RORCPOLBGAAKMT2AOPRL1 | |
| SCHEMBL22662766 | 0.83 | HRH3 (0.46) | RORCMEN1KMT2A | |
| SCHEMBL20003193 | 0.83 | RORC (0.59) | RORCPOLBGAAKMT2AOPRL1 | |
| SCHEMBL20002789 | 0.83 | RORC (0.67) | RORC | |
| SCHEMBL20002797 | 0.81 | RORC (0.64) | RORCMEN1KMT2AOPRL1 | |
| SCHEMBL20002892 | 0.80 | RORC (0.62) | RORC | |
| SCHEMBL20003101 | 0.79 | RORC (0.47) | RORCMEN1KMT2ACHRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |