Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27351775 | 0.81 | — | — | |
| SCHEMBL158602 | 0.77 | NSD2 (0.44) | CTSC | |
| SCHEMBL4606683 | 0.77 | KDM4E (0.33) | CTSCKCNH2LTB4RLTB4R2 | |
| Hydrochloric Acid SCHEMBL2003747 | 0.75 | NSD2 (0.42) | CTSC | |
| SCHEMBL4606679 | 0.75 | CTSC (0.31) | CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL15468676 | 0.75 | SMN1; SMN2 (0.34) | CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL16886292 | 0.75 | CNR1 (0.30) | — | |
| SCHEMBL23385891 | 0.70 | ALDH1A1 (0.33) | CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL1515589 | 0.70 | CTSC (0.37) | CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL971209 | 0.70 | CYP3A4 (0.41) | CTSCKCNH2LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |