Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002901 | 0.89 | RORC (0.53) | RORCNR1I2 | |
| SCHEMBL20002997 | 0.87 | RORC (0.67) | RORCNR1I2 | |
| SCHEMBL20002496 | 0.85 | RORC (0.54) | RORCNR1I2 | |
| SCHEMBL20002780 | 0.83 | RORC (0.70) | RORC | |
| SCHEMBL20002881 | 0.83 | RORC (0.70) | RORC | |
| SCHEMBL20002129 | 0.82 | RORC (0.61) | RORCNR1I2 | |
| SCHEMBL16886504 | 0.80 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL20002928 | 0.80 | RORC (0.67) | RORCNR1I2 | |
| SCHEMBL20002562 | 0.79 | RORC (0.70) | RORC | |
| SCHEMBL20002528 | 0.79 | RORC (0.70) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |