Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.38 |
| ▸ | HRH2 | P25021 | 6/20 | 0.38 |
| ▸ | HRH1 | P35367 | 6/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19864914 | 0.95 | ESR2 (0.52) | ESR2HRH3HRH2HRH1KCNH2 | |
| SCHEMBL9136281 | 0.86 | ESR2 (0.38) | ESR2HRH3KCNH2SLC6A2SLC6A4 | |
| SCHEMBL13804031 | 0.84 | ESR2 (0.47) | ESR2HRH3HRH2HRH1KCNH2 | |
| SCHEMBL11187396 | 0.80 | ESR2 (0.68) | ESR2HRH3KCNH2NPC1RAB9A | |
| SCHEMBL11187392 | 0.80 | ESR2 (0.68) | ESR2HRH3KCNH2NPC1RAB9A | |
| SCHEMBL170548 | 0.80 | ESR2 (0.53) | ESR2NPC1RAB9ADRD2MEN1 | |
| SCHEMBL29091934 | 0.79 | HRH3 (0.41) | ESR2HRH3KCNH2NPC1RAB9A | |
| SCHEMBL14649680 | 0.78 | HRH3 (0.54) | ESR2HRH3HRH2HRH1KCNH2 | |
| SCHEMBL11524401 | 0.78 | HRH3 (0.54) | ESR2HRH3HRH2HRH1KCNH2 | |
| SCHEMBL11524397 | 0.78 | HRH3 (0.54) | ESR2HRH3HRH2HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2792728-B1 | LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT, AND LIQUID CRYSTAL DISPLAY | DAINIPPON INK & CHEMICALS (JP) | 2018-03-28 | — | — | EP | disclosed |