Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12262722 | 1.00 | METAP1 (0.48) | METAP1METAP2CYP1A2SIGMAR1OPRM1 | |
| SCHEMBL22229853 | 0.98 | METAP1 (0.52) | METAP1METAP2CYP1A2SIGMAR1 | |
| SCHEMBL2062321 | 0.98 | METAP1 (0.52) | METAP1METAP2CYP1A2SIGMAR1 | |
| SCHEMBL11982905 | 0.95 | — | — | |
| SCHEMBL1678918 | 0.90 | — | — | |
| SCHEMBL30320701 | 0.90 | — | — | |
| SCHEMBL24831947 | 0.86 | CYP1A2 (0.48) | METAP1METAP2CYP1A2SIGMAR1OPRM1 | |
| SCHEMBL23259992 | 0.84 | CYP1A2 (0.52) | METAP1METAP2CYP1A2SIGMAR1OPRM1 | |
| SCHEMBL14105986 | 0.84 | CYP1A2 (0.52) | METAP1METAP2CYP1A2SIGMAR1OPRM1 | |
| SCHEMBL9376498 | 0.82 | SIGMAR1 (0.52) | METAP1METAP2CYP1A2SIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057912-A1 | FLUORESCENT COMPOUND COMPRISING A FLUOROPHORE CONJUGATED TO A pH -TRIGGERED POLYPEPTIDE | RHODE ISLAND COUNCIL ON POSTSECONDARY EDUCATION (US) | 2018-03-29 | — | — | WO | disclosed |