Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 9/20 | 0.45 |
| ▸ | AXL | P30530 | 8/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19373324 | 0.86 | FGFR2 (0.47) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL29822421 | 0.84 | FGFR2 (0.67) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL23617110 | 0.84 | FGFR2 (0.67) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL10269247 | 0.82 | MET (0.54) | FGFR2METAXLKDR | |
| SCHEMBL22521192 | 0.80 | FGFR2 (0.59) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL23617111 | 0.78 | RET (0.57) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL22521271 | 0.76 | AXL (0.48) | FGFR2PDGFRAMETAXLKDR | |
| SCHEMBL22521159 | 0.76 | MET (0.63) | FGFR2METAXLFLT3 | |
| SCHEMBL20216782 | 0.75 | MET (0.55) | METAXLFLT3 | |
| SCHEMBL18516581 | 0.75 | MET (0.64) | FGFR2METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299369-A1 | PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-03-28 | — | — | EP | disclosed |