Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 16/20 | 0.72 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608676 | 0.91 | OSBP (0.73) | OSBPOSBP2CYP19A1PTGS2 | |
| Schweinfurthin E SCHEMBL24867154 | 0.90 | OSBP (0.77) | OSBPOSBP2CYP19A1PTGS2 | |
| Schweinfurthin B SCHEMBL12042782 | 0.85 | OSBP (0.85) | OSBPOSBP2 | |
| Schweinfurthin B SCHEMBL847454 | 0.85 | OSBP (0.85) | OSBPOSBP2 | |
| SCHEMBL13076642 | 0.84 | OSBP (0.71) | OSBPOSBP2CYP19A1PTGS2 | |
| SCHEMBL12589142 | 0.84 | OSBP (0.68) | OSBPOSBP2CYP19A1 | |
| Schweinfurthin H SCHEMBL24867155 | 0.84 | OSBP (1.00) | OSBPOSBP2CYP19A1PTPN1 | |
| SCHEMBL12589198 | 0.83 | OSBP (0.67) | OSBPOSBP2CYP19A1 | |
| SCHEMBL30935456 | 0.83 | OSBP (0.70) | OSBPOSBP2CYP19A1PTGS2 | |
| SCHEMBL24867422 | 0.83 | OSBP (0.70) | OSBPOSBP2CYP19A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432466-B1 | SCHWEINFURTHINS AND USES THEREOF | US HEALTH (US) | 2018-03-28 | — | — | EP | disclosed |