Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 13/20 | 0.77 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608676 | 0.97 | OSBP (0.73) | OSBPOSBP2CYP19A1PTGS2ALOX5 | |
| Schweinfurthin B SCHEMBL847454 | 0.93 | OSBP (0.85) | OSBPOSBP2 | |
| Schweinfurthin B SCHEMBL12042782 | 0.93 | OSBP (0.85) | OSBPOSBP2 | |
| Vedelianin SCHEMBL30978359 | 0.91 | OSBP (0.84) | OSBPOSBP2CYP19A1 | |
| Vedelianin SCHEMBL30169535 | 0.91 | OSBP (0.84) | OSBPOSBP2CYP19A1 | |
| SCHEMBL24867422 | 0.91 | OSBP (0.70) | OSBPOSBP2CYP19A1PTGS2ALOX5 | |
| SCHEMBL30935456 | 0.91 | OSBP (0.70) | OSBPOSBP2CYP19A1PTGS2ALOX5 | |
| SCHEMBL13076642 | 0.91 | OSBP (0.71) | OSBPOSBP2CYP19A1PTGS2ALOX5 | |
| SCHEMBL20003838 | 0.90 | OSBP (0.72) | OSBPOSBP2CYP19A1PTGS2 | |
| SCHEMBL31547371 | 0.88 | OSBP (0.67) | OSBPOSBP2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327370-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-10-03 | — | — | US | claimed |
| EP-4363410-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | Centre National de la Recherche Scientifique (FR) | 2024-05-08 | — | — | EP | claimed |
| WO-2023275324-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-05 | — | — | WO | claimed |
| US-12427133-B2 | Combination therapies comprising schweinfurthin compounds for treating cancer | THE PENN STATE RESEARCH FOUNDATION (US) | 2025-09-30 | — | — | US | disclosed |
| US-20240327370-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-10-03 | — | — | US | disclosed |
| EP-4366827-A1 | NOVEL COMPOUNDS DERIVED FROM SCHWEINFURTHINS G, E AND F | Centre National de la Recherche Scientifique (FR) | 2024-05-15 | — | — | EP | disclosed |
| EP-4363410-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | Centre National de la Recherche Scientifique (FR) | 2024-05-08 | — | — | EP | disclosed |
| WO-2023280817-A1 | NOVEL COMPOUNDS DERIVED FROM SCHWEINFURTHINS G, E AND F | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-12 | — | — | WO | disclosed |
| WO-2023275324-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2023-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327370-A1 | PROCESS FOR THE BIOBASED SYNTHESIS OF SCHWEINFURTHINS G, K AND R | DCXR, SORD, GMFG | OSBP 3630/4885OSBP2 3611/4885CYP19A1 3110/4885 |
| US-12427133-B2 | Combination therapies comprising schweinfurthin compounds for treating cancer | CD274, PDCD1, PDCD1LG2 | OSBP 3812/4885OSBP2 4071/4885CYP19A1 3848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.