Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.56 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.54 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.54 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29962577 | 0.81 | ALK (0.81) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL898433 | 0.81 | ALK (0.81) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL20004437 | 0.79 | ALK (0.46) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL17448513 | 0.76 | ALK (0.85) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL30760746 | 0.75 | ALK (0.63) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL30760748 | 0.75 | ALK (0.70) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL18688912 | 0.74 | ALK (0.61) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL1703577 | 0.73 | ALK (0.79) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL29962786 | 0.73 | ALK (0.79) | ALKEML4SRPK2SRPK1KDR | |
| SCHEMBL18688863 | 0.73 | ALK (0.69) | ALKEML4SRPK2SRPK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |