Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.46 |
| ▸ | SRPK1 | Q96SB4 | 9/20 | 0.46 |
| ▸ | SRPK2 | P78362 | 7/20 | 0.46 |
| ▸ | EML4 | Q9HC35 | 7/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004216 | 0.88 | SRPK1 (0.60) | ALKSRPK1SRPK2EML4DYRK3 | |
| SCHEMBL20004887 | 0.88 | ALK (0.49) | ALKSRPK1SRPK2EML4DYRK3 | |
| SCHEMBL20004219 | 0.79 | ALK (0.56) | ALKSRPK1SRPK2EML4KDR | |
| SCHEMBL20004194 | 0.77 | SRPK1 (0.60) | ALKSRPK1SRPK2EML4DYRK3 | |
| SCHEMBL20004398 | 0.77 | SRPK1 (0.74) | ALKSRPK1SRPK2EML4DYRK3 | |
| SCHEMBL24852169 | 0.76 | SRPK1 (0.58) | ALKSRPK1SRPK2EML4DYRK3 | |
| SCHEMBL20366734 | 0.75 | ALK (0.49) | ALK | |
| SCHEMBL22369276 | 0.74 | ALK (0.55) | ALKSRPK1SRPK2EML4KDR | |
| SCHEMBL21443147 | 0.72 | ALK (0.45) | ALKSRPK1SRPK2EML4 | |
| SCHEMBL7809841 | 0.72 | ALK (0.50) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |