Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537769 | 0.83 | SNCA (0.71) | SNCAMAPTAPP | |
| SCHEMBL20004518 | 0.82 | SNCA (1.00) | SNCAMAPTAPP | |
| SCHEMBL20005053 | 0.82 | SNCA (0.76) | SNCAMAPTGRM5 | |
| SCHEMBL21192533 | 0.80 | SNCA (0.53) | SNCAMAPT | |
| SCHEMBL21115232 | 0.79 | SNCA (0.93) | SNCAMAPTAPP | |
| SCHEMBL20005086 | 0.79 | SNCA (0.58) | SNCAMAPTGRM5 | |
| SCHEMBL21147622 | 0.79 | SNCA (0.53) | SNCAMAPT | |
| SCHEMBL20005047 | 0.79 | SNCA (0.53) | SNCAMAPT | |
| SCHEMBL20005049 | 0.78 | SNCA (0.63) | SNCAMAPT | |
| SCHEMBL21170669 | 0.78 | GRM5 (0.47) | SNCAMAPTGRM5GRM4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |