Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13591281 | 0.83 | AKR1C3 (0.47) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL82680 | 0.83 | MEN1 (0.69) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2155630 | 0.81 | MEN1 (0.68) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2453453 | 0.81 | MAPT (0.59) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL974007 | 0.81 | POLB (0.54) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1926789 | 0.81 | MAPT (0.58) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6152910 | 0.81 | MAPT (0.58) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL941084 | 0.81 | ALDH1A1 (0.65) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2103070 | 0.81 | CYP2C9 (0.72) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL20887246 | 0.80 | SMN1; SMN2 (0.51) | POLBMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |