Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999463 | 0.96 | TSHR (0.49) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20005244 | 0.94 | RARB (0.40) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999351 | 0.94 | TSHR (0.45) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20006853 | 0.93 | FFAR1 (0.40) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20005274 | 0.92 | TSHR (0.43) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20004889 | 0.91 | RARB (0.39) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999453 | 0.90 | HSD17B10 (0.50) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20004744 | 0.90 | TSHR (0.46) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20004902 | 0.90 | RARB (0.37) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999422 | 0.89 | TSHR (0.49) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |