Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MMP25 | Q9NPA2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999387 | 0.96 | HSD17B10 (0.51) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999390 | 0.95 | FFAR1 (0.39) | TSHRHSD17B10FFAR1SKP2PTPN11 | |
| SCHEMBL14773018 | 0.93 | TSHR (0.46) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999363 | 0.92 | HSD17B10 (0.44) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20005274 | 0.91 | TSHR (0.43) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999384 | 0.91 | TSHR (0.51) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999462 | 0.90 | TSHR (0.44) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL20004483 | 0.90 | TSHR (0.44) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL14846047 | 0.90 | HSD17B10 (0.51) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL19999351 | 0.89 | TSHR (0.45) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |