Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004355 | 0.84 | MEN1 (0.53) | APPALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL14280621 | 0.82 | KDM4E (0.41) | APPPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL12451533 | 0.81 | APP (0.47) | APPALDH1A1PSMB1PSMB5TDP1 | |
| SCHEMBL10457449 | 0.78 | APP (0.59) | APPALDH1A1 | |
| SCHEMBL9871129 | 0.78 | APP (0.47) | APPALDH1A1 | |
| SCHEMBL21467379 | 0.77 | CYP2C9 (0.55) | ALDH1A1MEN1KMT2A | |
| SCHEMBL14280602 | 0.77 | KDM4E (0.47) | APPPSMB1PSMB5MEN1KMT2A | |
| SCHEMBL14441203 | 0.74 | MEN1 (0.56) | APPALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL20004342 | 0.74 | APP (0.57) | APPMEN1KMT2ATDP1 | |
| SCHEMBL21467376 | 0.73 | MEN1 (0.54) | APPMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |