SCHEMBL9871129

SCHEMBL9871129

FCCOc1ccc(C(F)F)cc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APP P05067 7/20 0.47
ALDH1A1 P00352 1/20 0.44
MRGPRX4 Q96LA9 1/20 0.41
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
KCNH2 Q12809 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10457449 0.83 APP (0.59) APPALDH1A1KCNH2
SCHEMBL20004355 0.81 MEN1 (0.53) APPALDH1A1
SCHEMBL16454946 0.81 SLC2A1 (0.53)
SCHEMBL10456781 0.78 APP (0.47) APPALDH1A1MRGPRX4KCNH2
SCHEMBL20004498 0.78 APP (0.47) APPALDH1A1
SCHEMBL12451533 0.78 APP (0.47) APPALDH1A1
SCHEMBL10458215 0.77 APP (0.53) APPALDH1A1
SCHEMBL28356452 0.76 NR5A1 (0.59)
SCHEMBL10305096 0.76 TAAR1 (0.52) APPALDH1A1DRD2
SCHEMBL23272164 0.76 ALDH1A1 (0.41) APPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5012004-A Ether compounds and their production, and insecticidal and/or acaricidal compositions containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-04-30 US disclosed
EP-0315370-A2 Ether compounds and their production, and insecticidal and/or acaricidal compositions containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-05-10 EP disclosed