Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17636118 | 0.85 | ALK (0.54) | ALK | |
| SCHEMBL897714 | 0.84 | ALK (0.57) | ALK | |
| SCHEMBL20004692 | 0.82 | ALK (0.52) | ALK | |
| SCHEMBL897165 | 0.79 | ALK (0.62) | ALK | |
| SCHEMBL10272274 | 0.71 | ALK (0.59) | ALK | |
| SCHEMBL20004558 | 0.71 | ALK (0.63) | ALK | |
| SCHEMBL1703864 | 0.70 | ALK (0.59) | ALK | |
| SCHEMBL20004495 | 0.70 | ALK (0.58) | ALK | |
| SCHEMBL897365 | 0.70 | ALK (1.00) | ALK | |
| SCHEMBL896771 | 0.69 | ALK (0.74) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |