Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21443222 | 0.90 | ALK (0.48) | ALK | |
| SCHEMBL897638 | 0.82 | ALK (0.63) | ALK | |
| SCHEMBL21443232 | 0.77 | NCOA1 (0.31) | — | |
| SCHEMBL25446834 | 0.76 | ALK (0.61) | ALK | |
| SCHEMBL20004253 | 0.75 | CA1 (0.32) | ALK | |
| SCHEMBL20366386 | 0.74 | ALK (0.73) | ALK | |
| SCHEMBL20366607 | 0.74 | ALK (0.62) | ALK | |
| SCHEMBL21443153 | 0.73 | ALK (0.59) | ALK | |
| SCHEMBL20004266 | 0.73 | ALK (0.61) | ALK | |
| SCHEMBL20366569 | 0.73 | ALK (0.59) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |