Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 18/20 | 0.66 |
| ▸ | SRPK2 | P78362 | 3/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 3/20 | 0.39 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897881 | 0.83 | ALK (0.68) | ALK | |
| SCHEMBL897451 | 0.80 | ALK (0.64) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL7818333 | 0.80 | ALK (1.00) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL897318 | 0.79 | ALK (0.62) | ALK | |
| SCHEMBL898134 | 0.78 | ALK (0.69) | ALKSRPK2SRPK1EML4 | |
| SCHEMBL7807289 | 0.77 | ALK (0.50) | ALK | |
| SCHEMBL1755894 | 0.76 | ALK (0.57) | ALKSRPK2SRPK1 | |
| SCHEMBL20004814 | 0.74 | ALK (0.75) | ALK | |
| SCHEMBL27087593 | 0.74 | ALK (0.57) | ALK | |
| SCHEMBL20004268 | 0.73 | ALK (0.56) | ALKSRPK2SRPK1EML4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2975024-B1 | TETRACYCLIC COMPOUNDS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2018-03-28 | — | — | EP | disclosed |