Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ADK | P55263 | 8/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537667 | 0.86 | SNCA (0.59) | SNCAMAPTADKAPP | |
| SCHEMBL22537615 | 0.83 | SNCA (0.56) | SNCAMAPTADKAPP | |
| SCHEMBL22537823 | 0.79 | SNCA (0.59) | SNCAMAPTADKAPP | |
| SCHEMBL22537780 | 0.75 | SNCA (0.49) | SNCAMAPTADKAPP | |
| SCHEMBL20004997 | 0.72 | SNCA (1.00) | SNCAMAPTADKAPP | |
| SCHEMBL22537866 | 0.66 | SNCA (0.48) | SNCAMAPTADK | |
| SCHEMBL2555531 | 0.62 | APP (0.57) | SNCAMAPTADKAPP | |
| SCHEMBL22537806 | 0.62 | SNCA (0.52) | SNCAMAPT | |
| SCHEMBL770159 | 0.62 | ALDH1A1 (0.65) | SNCAMAPTADKAPP | |
| SCHEMBL10300053 | 0.62 | ALDH1A1 (0.65) | SNCAMAPTADKAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |