Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 12/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ADK | P55263 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005042 | 0.75 | SNCA (0.46) | SNCAMAPTADKAPP | |
| SCHEMBL21147267 | 0.74 | SNCA (0.51) | SNCAMAPTADKAPP | |
| SCHEMBL20004510 | 0.69 | SNCA (0.47) | SNCAMAPTADKAPP | |
| SCHEMBL20004677 | 0.68 | SNCA (1.00) | SNCAMAPTAPP | |
| SCHEMBL20005039 | 0.66 | SNCA (0.46) | SNCAMAPTADKAPP | |
| SCHEMBL20005021 | 0.66 | SNCA (1.00) | SNCAMAPTAPP | |
| SCHEMBL20004518 | 0.66 | SNCA (1.00) | SNCAMAPTAPP | |
| SCHEMBL10300053 | 0.65 | ALDH1A1 (0.65) | SNCAMAPTADKAPP | |
| SCHEMBL770159 | 0.65 | ALDH1A1 (0.65) | SNCAMAPTADKAPP | |
| SCHEMBL20004394 | 0.65 | SNCA (0.42) | SNCAMAPTADKAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |