Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | SNCA | P37840 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537684 | 0.77 | KDM4E (0.43) | MAPTSNCAKDM4EMEN1KMT2A | |
| SCHEMBL20004691 | 0.69 | APP (0.41) | MAPTSNCAAPP | |
| SCHEMBL20004552 | 0.67 | SNCA (1.00) | MAPTSNCAKDM4ETP53MEN1 | |
| SCHEMBL12454616 | 0.66 | KDM4E (0.62) | MAPTKDM4ETP53MEN1KMT2A | |
| SCHEMBL20232427 | 0.64 | KDM4E (0.63) | MAPTKDM4ETP53MEN1KMT2A | |
| SCHEMBL820477 | 0.64 | KDM4E (0.55) | MAPTKDM4ETP53MEN1KMT2A | |
| SCHEMBL10979112 | 0.63 | MAPT (0.55) | MAPTSNCAKDM4ETP53MEN1 | |
| SCHEMBL16438246 | 0.62 | KDM4E (0.71) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL8618790 | 0.62 | MAPT (0.55) | MAPTSNCAKDM4ETP53MEN1 | |
| SCHEMBL22537764 | 0.61 | APP (0.35) | MEN1KMT2AALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |