Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.41 |
| ▸ | ADK | P55263 | 15/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SNCA | P37840 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005008 | 0.69 | MAPT (0.51) | APPMAPTSNCA | |
| SCHEMBL20001579 | 0.66 | APP (0.44) | APPADKMAPT | |
| SCHEMBL22537764 | 0.64 | APP (0.35) | APP | |
| SCHEMBL770159 | 0.61 | ALDH1A1 (0.65) | APPADKMAPTSNCA | |
| SCHEMBL10300053 | 0.61 | ALDH1A1 (0.65) | APPADKMAPTSNCA | |
| SCHEMBL11089419 | 0.61 | APP (0.60) | APPMAPT | |
| SCHEMBL15591967 | 0.58 | APP (0.44) | APP | |
| SCHEMBL8028758 | 0.57 | ALDH1A1 (0.55) | APPADKMAPTSNCA | |
| SCHEMBL13247229 | 0.56 | RELA (0.63) | APPMAPT | |
| SCHEMBL18526935 | 0.56 | ALDH1A1 (0.48) | APPADKMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |