Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 8/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.44 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MELK | Q14680 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004279 | 0.84 | SNCA (0.68) | SNCAMAPTRIPK1DAO | |
| SCHEMBL20005065 | 0.81 | SNCA (0.59) | SNCAMAPTRIPK1 | |
| SCHEMBL20005072 | 0.81 | SNCA (0.68) | SNCAMAPTRIPK1DAO | |
| SCHEMBL20005138 | 0.81 | SNCA (0.72) | SNCAMAPTRIPK1DAO | |
| SCHEMBL20005052 | 0.80 | SNCA (0.64) | SNCAMAPTRIPK1 | |
| SCHEMBL20005045 | 0.80 | SNCA (0.72) | SNCAMAPTRIPK1ACACB | |
| SCHEMBL22537623 | 0.80 | SNCA (0.57) | SNCAMAPTRIPK1 | |
| SCHEMBL21147053 | 0.79 | SNCA (0.69) | SNCAMAPTRIPK1DAO | |
| SCHEMBL20004547 | 0.79 | MAPT (0.58) | SNCAMAPTRIPK1ASIC3DAO | |
| SCHEMBL20005050 | 0.79 | SNCA (0.52) | SNCAMAPTRIPK1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |