Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 12/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21147053 | 0.85 | SNCA (0.69) | SNCAMAPTDAORIPK1CCNB2 | |
| SCHEMBL22537818 | 0.85 | SNCA (0.61) | SNCAMAPTDAORIPK1CCNB2 | |
| SCHEMBL20004279 | 0.85 | SNCA (0.68) | SNCAMAPTDAORIPK1ALDH1A1 | |
| SCHEMBL20005072 | 0.85 | SNCA (0.68) | SNCAMAPTDAORIPK1CCNB2 | |
| SCHEMBL20004519 | 0.84 | SNCA (0.67) | SNCAMAPTRIPK1CCNB2CDK1 | |
| SCHEMBL20004389 | 0.84 | SNCA (1.00) | SNCAMAPTDAORIPK1CCNB2 | |
| SCHEMBL22537701 | 0.82 | SNCA (0.56) | SNCAMAPT | |
| SCHEMBL20005009 | 0.81 | SNCA (0.64) | SNCAMAPTDAORIPK1 | |
| SCHEMBL22930176 | 0.80 | SNCA (0.77) | SNCAMAPTDAORIPK1CCNB2 | |
| SCHEMBL342758 | 0.79 | MAPT (0.60) | SNCAMAPTDAORIPK1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |