Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004574 | 0.82 | SNCA (0.76) | SNCAMAPT | |
| SCHEMBL22537777 | 0.77 | SNCA (0.79) | SNCAMAPT | |
| SCHEMBL20005089 | 0.77 | SNCA (0.79) | SNCAMAPT | |
| SCHEMBL20004553 | 0.77 | SNCA (1.00) | SNCAMAPT | |
| SCHEMBL20005138 | 0.77 | SNCA (0.72) | SNCAMAPTALDH1A1 | |
| SCHEMBL22930176 | 0.76 | SNCA (0.77) | SNCAMAPT | |
| SCHEMBL21115283 | 0.75 | MAPT (0.34) | SNCAMAPTF2PRSS2CTRC | |
| SCHEMBL20004597 | 0.75 | SNCA (0.94) | SNCAMAPT | |
| SCHEMBL20004389 | 0.73 | SNCA (1.00) | SNCAMAPT | |
| SCHEMBL19995089 | 0.73 | MAPT (0.38) | MAPTF2PRSS2CTRCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |