Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004718 | 0.85 | SNCA (0.60) | SNCAALKMAPTTP53STAT6 | |
| SCHEMBL20004511 | 0.84 | SNCA (0.57) | SNCAALKMAPTALDH1A1LMNA | |
| SCHEMBL20005123 | 0.82 | SNCA (0.56) | SNCAALKMAPTKDM4ETP53 | |
| SCHEMBL20005047 | 0.79 | SNCA (0.53) | SNCAALKMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21147622 | 0.77 | SNCA (0.53) | SNCAALKMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20005044 | 0.75 | SNCA (0.55) | SNCAMAPTALDH1A1LMNAGAA | |
| SCHEMBL22537769 | 0.75 | SNCA (0.71) | SNCAMAPT | |
| SCHEMBL20004447 | 0.74 | SNCA (0.70) | SNCAMAPT | |
| SCHEMBL20004518 | 0.74 | SNCA (1.00) | SNCAMAPT | |
| SCHEMBL20005086 | 0.73 | SNCA (0.58) | SNCAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |