Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 5/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 2/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537592 | 0.90 | MAPT (0.34) | MAPTSNCAHCAR2MAOBSGMS2 | |
| SCHEMBL20005050 | 0.76 | SNCA (0.52) | MAPTSNCAHCAR2MAOBSGMS2 | |
| SCHEMBL22537834 | 0.68 | HCAR2 (0.37) | MAPTSNCAHCAR2SGMS2ALDH1A1 | |
| SCHEMBL20004335 | 0.68 | IDO1 (0.42) | HCAR2MAOBRAB9AKDM4EMAOA | |
| SCHEMBL20004514 | 0.66 | SNCA (0.58) | MAPTSNCARIPK1 | |
| SCHEMBL22537871 | 0.65 | MAPT (0.39) | MAPTSNCARIPK1 | |
| SCHEMBL20005065 | 0.62 | SNCA (0.59) | MAPTSNCARIPK1 | |
| SCHEMBL342758 | 0.61 | MAPT (0.60) | MAPTSNCARIPK1 | |
| SCHEMBL20005072 | 0.61 | SNCA (0.68) | MAPTSNCARIPK1 | |
| SCHEMBL22537548 | 0.61 | SNCA (0.46) | SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |