Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005141 | 0.89 | SNCA (0.63) | SNCAMAPTKDM4ESMN1; SMN2PIK3CA | |
| SCHEMBL22537777 | 0.77 | SNCA (0.79) | SNCAMAPT | |
| SCHEMBL20005119 | 0.76 | SNCA (0.50) | SNCAMAPTKDM4ESMN1; SMN2KIT | |
| SCHEMBL20004443 | 0.75 | SNCA (0.60) | SNCAMAPTKDM4ESMN1; SMN2PIK3CA | |
| SCHEMBL20005180 | 0.73 | SNCA (0.57) | SNCAMAPTKDM4ESMN1; SMN2KIT | |
| SCHEMBL20004470 | 0.67 | SNCA (0.81) | SNCAMAPT | |
| SCHEMBL20004553 | 0.66 | SNCA (1.00) | SNCAMAPT | |
| SCHEMBL20005089 | 0.66 | SNCA (0.79) | SNCAMAPT | |
| SCHEMBL20004574 | 0.64 | SNCA (0.76) | SNCAMAPTGRM4 | |
| SCHEMBL20004597 | 0.64 | SNCA (0.94) | SNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |