Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 4/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005123 | 0.87 | SNCA (0.56) | SNCAMAPTPIK3CAMTORACACB | |
| SCHEMBL22537543 | 0.81 | SNCA (0.41) | SNCAMAPTACACBALKKDM4E | |
| SCHEMBL22537701 | 0.79 | SNCA (0.56) | SNCAMAPTKIT | |
| SCHEMBL22537820 | 0.73 | SNCA (0.51) | SNCAMAPTACACBKIT | |
| SCHEMBL22537877 | 0.73 | SNCA (0.75) | SNCAMAPT | |
| SCHEMBL20004718 | 0.73 | SNCA (0.60) | SNCAMAPTALKMAPK1 | |
| SCHEMBL20005066 | 0.72 | SNCA (0.58) | SNCAMAPTALKKDM4EMEN1 | |
| SCHEMBL21147082 | 0.71 | CYP2C9 (0.38) | PIK3CAMTORACACBMEN1ALDH1A1 | |
| SCHEMBL20004511 | 0.71 | SNCA (0.57) | SNCAMAPTPIK3CAALKKCNH2 | |
| SCHEMBL20005047 | 0.69 | SNCA (0.53) | SNCAMAPTACACBALKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |