Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004453 | 0.78 | SNCA (0.36) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL20005013 | 0.78 | GRM5 (0.40) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL22537854 | 0.76 | — | — | |
| SCHEMBL21147086 | 0.73 | GRM5 (0.41) | GRM5CHRNB2CHRNA4 | |
| SCHEMBL21147289 | 0.73 | PIK3CA (0.38) | IKBKB | |
| SCHEMBL21147267 | 0.71 | SNCA (0.51) | — | |
| SCHEMBL22537807 | 0.69 | ACACB (0.34) | — | |
| SCHEMBL22537813 | 0.67 | APP (0.33) | — | |
| SCHEMBL22537542 | 0.67 | SNCA (0.39) | — | |
| SCHEMBL22537774 | 0.66 | APP (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |